A wide array of methodologies for collecting, transporting, and storing biological samples has been extensively documented, yet the commonly utilized technique for preserving tissue samples often leads to significant DNA degradation. The integrity of biological samples, characterized by stable and non-degraded biomolecules, is crucial for both quantitative and qualitative downstream processes. NucleoSafe emerges within the realms of life science, molecular biology, and biomedical research, introducing an innovative approach and agent for collecting, transporting, and storing biological samples. NucleoSafe ensures the preservation and integrity of tissue sample contents, especially DNA, by effectively mitigating degradation before subsequent downstream processing steps. Unlike conventional methods, this preservation technique eliminates the necessity for ultra-low temperature storage, enabling preservation at ambient temperatures.

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